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KMID : 1094020150320050422
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Journal of Veterinary Clinics
2015 Volume.32 No. 5 p.422 ~ p.425
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Effect of Medetomidine and Combination of Medetomidine/tiletamine/ zolazepam and Medetomidine/tiletamine/zolazepam/tramadol on Echocardiographic Cardiac Contractility in Dogs
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Suh Sang-IL
Kim Tae-Jun
Lee Eun-Chan
Hyun Chang-Baig
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Abstract
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This study evaluated the myocardial performance on echocardiography after the sedation/anesthesia of medetomidine (D), the combination of medetomidine and tiletamine/zolazepam (DZ), and the combination of medetomidine, tiletamine/zolazepam and tramadol (DZT) in Beagle dogs. Ten healthy adult Beagle dogs (weighing 8.6 ± 1.0 kg) were enrolled in this study. Heart rate (HR), fractional shortening (%FS), left ventricular ejection fraction (%LVEF), stroke volume (SV), cardiac output (CO), left ventricular internal diameter in systole (LVIDs) and left ventricular internal diameter in diastole (LVIDd) using M-mode echocardiography were measured prior to anesthesia, then every 10 min for 60 min. The HR, %FS, %LVEF, SV and CO were significantly decreased during sedation/ anesthesia with D, DZ and DZT combination of anesthesia. Although those anesthetic protocols provided acceptable quality of sedation/anesthesia, levels of cardiovascular suppression were substantial and persistent and thus the continuous monitoring on vital signs should be accompanied in any situation. Close attention is required for dogs with pre-existing heart diseases, when those anesthetic protocols were applied.
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KEYWORD
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medetomidine, anesthesia, Domitor, tiletamine, tramadol, dog
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